The Deep Look Into DNP
By: The Steroid Guru
DNP is a controversial chemical in the bodybuilding world that has received its praise for its ability shed body fat in a short amount of time, but it has also received its fair share of criticism. The chemical 2,4 dinitrophenol, (also known as DNP) probably deserves the bashing it has received. Numerous people have died from ingesting this chemical as a means to lose body fat very quickly.
It has been estimated that over 60 people have died from using DNP. The views from people that are familiar with DNP have a very strong contrast. Many believe that the deaths resulting from DNP use occur only when the chemical is abused, and others believe that this drug can be deadly even when taken along the lines of the strict protocol that has been suggested for decades. I am not here to suggest that either side is right or wrong, but merely to state the facts.
The chemical known as DNP works by inhibiting the F0F1 adenosine triphosphate, or ATP, synthase molecule in the body. ATP is used in cellular energy transfer, transferring energy within cells. The body converts adenosine diphosphate into ATP and converts it back to adenosine phosphate after being used. DNP inhibits this synthesis and energy is expelled as heat.
This results in a metabolic increase of about 50 percent, which has resulted fat loss in the range of a pound of body fat per day. This is something that would spark an interest in any dieter.
DNP has been in production for almost a century and it was first used on an industrial scale in French munitions factories during the First World War. It was mixed with picric acid to make explosives, and workers that were exposed to DNP when making explosives, experienced weight loss, elevated body temperature, and excessive sweating. During this time, there was not much known about the risk associated with DNP exposure and many deaths occurred due to this lack of knowledge.
A Stanford University study conducted in 1931 showed that DNP had the ability to dramatically drop body fat in a short period of time, and this study led to DNP finding its way into many diet potions and medications. The Federal Drug Administration wasn’t founded until 1906, and when DNP was being used as a diet medication, this organization didn’t have the ability to monitor what was being used and sold to the population as it does today. Keep in mind that this was a time when amphetamines were not a controlled drug and was commonly sold under the trade name Benzadrine as a decongestant.
2,4 dinitrophenol is a different animal than all the substances that have been used for weight loss over the years. Today, it is used in the manufacturing of dyes and wood preservatives, and it is also used as a pesticide. Generally, most drugs that have been used for fat loss with bodybuilders have had some medical use at one time, except for DNP. It seems that someone would have to pretty ballsy to ingest a chemical that is manufactured as a pesticide or explosive, or which has been known to cook a person from the inside out. The known ability of how DNP melts fat has made many people ignore these facts.
So, you’re probably wondering how to take this compound and how do you get those most out of it with the least side, right?
I have a conservative stance on when to use DNP, how much to use, and how long to use it.
Some people argue that DNP should be used on cycle so as to protect muscle. My contention is that DNP makes you feel like crap, and it can detract from lifting at your best while on cycle. If I am on cycle I want to be lifting hard and I do not want to worry about energy levels or heat stroke.
Other people argue that DNP should be used well after PCT. My only concern would be low energy levels and possible T3 issues. These concerns are manageable via things like ECA stacks and T3 supplementation.
My most preferred time to run DNP is when I start PCT. I still have energy and strength from my cycle and I avoid the whole catabolic post cycle phase. In addition, I have a nice little anabolic rebound at the end of my DNP run and I get to see the results from all my hard work on gear.
DNP is cumulative and it takes three weeks to clear your system. Do not bump up your dose because you think you can handle more. Do not use drugs or drink alcohol.
Please note that you do not need to “feel” DNP for it to be working. People have different tolerance levels, even for poisons. You can only get so much DNP into your system (before you die), so you can choose to take a higher dose short cycle or lower dose long cycle. Regardless, by the end of the cycle you will feel the heat and toxicity.
Low Dose Long Cycle
Start with a dose of 200mg per day [100 mg every morning / 100 mg
every evening]. Run it for two or three weeks.
Day 1 – 14: 200 mg ED
Day 15 – 21: 200 mg ED*
*Experienced users may choose to run the cycle for an additional week.
Total DNP consumption for long cycle: (2,800 to 4,200 mg)
High Dose Short Cycle
Start with a dose of 200 mg per day [100 mg every morning / 100 mg
every evening]. Within 2 to 4 days you should know if you have an allergy.
Day 1 – 4: 200 mg ED
Day 5 – 9: 400 mg ED
Day 10 – 11: 400 mg ED*
*Experienced users may choose to go above the max recommended daily dose of 400 mg
and run the cycle for an additional couple of days.
Total DNP consumption for short cycle: (2,800 to 4,000 mg)
What are common sides to DNP?
What food and supplements should I take while on a DNP cycle?
You may lose your senses of taste and smell so this is a good time to teach yourself how to eat without using condiments and all the other crap you don’t need.