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The "truth" about GHRP-6 & 2 - 5mg
Ghrelin: The “Hunger Hormone” Explained
What is Ghrelin?
Ghrelin is a hormone produced in the gut. It is often termed the hunger hormone, and sometimes called lenomorelin.
It travels through your bloodstream and to your brain, where it tells your brain to become hungry and seek out food.
Ghrelin’s main function is to increase appetite. It makes you consume more food, take in more calories and store fat.
The graph below shows how rats injected with the hormone had a rapid increase in weight.
In addition, it affects your sleep/wake cycle, reward-seeking behavior, taste sensation and carbohydrate metabolism.
This hormone is produced in your stomach and secreted when your stomach is empty. It enters the bloodstream and affects a part of the brain known as the hypothalamus,
which governs your hormones and appetite.
The higher your levels, the hungrier your get. The lower your levels, the more full you feel and the easier it is to eat fewer calories.
So if you want to lose weight, lowering your ghrelin levels can be beneficial.
Ghrelin may sound like a terrible, diet-wrecking hormone. However, in the past it played a role in survival by helping people maintain a healthy level of body fat.
These days, if you under-eat or struggle to gain weight, higher ghrelin levels may help you consume more food and calories per day.
Bottom Line: Ghrelin is a hormone that sends a signal to your brain to feel hungry. It plays a key role in regulating calorie intake and body fat levels.
Ghrelin levels typically rise before a meal, when your stomach is empty. Then they decrease shortly after, when your stomach is full.
While you might assume obese people have higher levels, they may just be more sensitive to its effects.
In fact, some research shows their levels are actually lower than in lean people.
Other research suggests that obese people may have an overly active ghrelin receptor, known as GHS-R,
which leads to increased calorie intake.
Yet regardless of how much body fat you have, ghrelin levels increase and make you hungry when you start a diet.
This is a natural response by your body, which tries to protect you from starvation.
During a diet, your appetite increases and your levels of the “fullness hormone” leptin go down. Your metabolic rate also tends to decrease significantly,
especially when you restrict calories for long periods of time.
For obvious reasons, these adaptations can make it significantly harder to lose weight and keep it off.
Your hormones and metabolism adjust to try to re-gain all the weight you lost.
Growth hormone releasing 6, more commonly known as GHRP 6, is a popular hormone. Basically, it is a hexapeptide composed of a 6 amino acids chain.
It is one of the numerous synthetic metenkephalin analogs which functions through incorporating manmade D amino acids. This is a germ-free, non-pyrogenic,
lyophilized powder that is administered via the subcutaneous or intramuscular route. GHRP 6 is an effective human growth hormone secretagogue (GHS_.
Secretagogue is a name given to substances which prompts secretion of another substance. In this case, GHRP 6 produces growth hormones.
These have need widely used for a range of health promotion and clinical activities.
For example, GHRP 6 helps in the production of growth hormones the same way the body naturally produces its own growth hormone reserves.
It also provides similar functions on the skin, joints and muscle mass. Moreover, it has the ability to treat as well as undo the effects of deficient human growth hormone.
Authorised and legitimate use of hormone replacement therapy is an excellent method of ensuring a healthier and longer life coupled with improved general well-being.
GHRP 6 is one of those novel that are able to promote increased energy and vigor. Despite this, it is important to know that GHRP 6 I distinctive from other growth hormone releasing .
Note that it does not have any mechanism of action on the receptor of GHRH; rather, it mainly acts on the HGH secretagogoue receptor.
This HGH secretagogou receptor is also known as ghrelin receptor. Ghrelin is a very powerful substance that is able to stimulate the release of growth hormones from the pituitary gland.
It is also known as an important protector of neurons.
When should you use GHRP 6?
GHRP 6 is most commonly used for growth hormone replacement therapy. It is normally chosen by users because of the obvious cost advantage it offers.
Growth hormones are restricted by stringent laws hence, more and more people are turning in to GHRP 6 use. GHRP 6 is used to enhance skin and improve increase muscle gain and fat loss.
It is also used in conjunction with other anabolic steroids to promote greater synergistic effects which includes increased recovery from injuries.
What makes GHRP 6 a unique and useful is that, you longer need to cycle it to receive all the benefits it offers.
You may use it for prolonged periods of time for any of the abovementioned reasons.
However, you must ensure to limit the dosage to the minimum suggested dosage range when you intent to use it on an ongoing basis.
Synergistic effects of GHRH and GHRH 6
GHRP 6 has the ability to promote increased production of growth hormones even when used alone.
A single dose of GHRP 6 is able to increase growth hormones in the body as compared to a growth hormone releasing hormone taken at the same time.
However, if you combine both GHRH and GHRP 6, only about a third or a half in as much as GHRP 6 is required for you to obtain the same amount of increase in growth hormone production. For this reason,
it is common for users to combine GHRH with GHRP. Users prefer to use CJC 1295 without DAC or Modified GRF 1-29 alongside GHRP 6
GHRP 6: A ghrelin mimetic
All GHRPs, including GHRP 6 are ghrelin mimetics. Ghrelin is a hormone released by stomach cells in response to fasting.
Both ghrelin mimetics and ghrelin function through activating ghrelin receptors which are also known as growth hormone secretagogue receptor or GHS-R1a.
Increased levels of ghrelin improve growth hormone levels through stimulating ghrelin receptors in the pituitary gland.
Administration of any GHRP or GHRP 6 stimulates the release of growth hormone. It acts similarly with ghrelin.
However, the effect is greater. You may be able to achieve supraphysiological growth hormone levels through proper dosing of GHRP 6.
Benefits of ghrelin
Ghrelin has many functions in the body aside from stimulating the release of growth hormones in the body. It has the ability to protect the heart, increase appetite, decrease inflammation, promote healing, improve fat reduction as well as protect the cells from oxidative damage. It also has the ability to improve production of cortisol through increasing prolactin and ACTH.
Note however that ghrelin activity is comparable to what usually occurs during fasting.
Ghrelin has never been used to as a drug to enhance performance unlike that of GHRPs. Use of GHRPs as a performance-enhancing drug was documented and researched extensively.
In particular, GHRP 6 is effective in treating tendonitis which might be due to its ability to activate the ghrelin receptor.
Fasting is known to provide a range of beneficial effects in the body aside from fat loss. Similarly,
it may be quite true that elevation of ghrelin levels may provide health benefits such as healing and anti-inflammatory effect.
Hence, proper dosage and cycling of GHRP 6 to improve ghrelin levels may also provide the above benefits.